Lorix Plus Lotion

✔️ Uses of Lorix Plus Lotion

• Scabies
• Pediculosis
• Crab louse infections

✔️ How does Lorix Plus Lotion work?

Permethrin works by killing the tiny insects (mites) and their eggs, which cause scabies. It also kills head lice that attach to your scalp and irritate it.

Crotamiton is an antiparasitic which works by killing the tiny insects (mites) and their eggs, which cause scabies.

✔️ Side Effects of Lorix Plus Lotion

There have been isolated complaints of a burning or stinging feeling that fades rapidly. This is often modest and more common in people with severe scabies. Skin irritation symptoms such as rash or itching, erythema, edema, and eczema are transient. These are widely accepted as part of the scabies' natural history.

✔️ Quick Suggestions:

• Lorix Plus Lotion is prescribed for the treatment of scabies( a condition where tiny insects infest and irritate your skin).
• It should be used as per the dose and duration suggested by your doctor.
• If the condition persists after 14 days of treatment then the doctor may suggest another treatment.
• Apply a thin layer of this medicine all over the body and leave it for 8-14 hours before taking a bath or shower.
• Avoid getting it in your eyes, nose, or mouth. If this happens, rinse with water immediately.

✔️ Indication of Lorix Plus Lotion

Scabies is a contagious skin condition caused by tiny, burrowing mites known as Sarcoptes scabiei that live on your skin. This can cause intense itching in the affected area. Lorix Plus Lotion is used in the treatment of scabies.

• Pruritic skin disorders

Lorix Plus Lotion is used in the treatment of pruritic skin (itchy skin) conditions such as dermatitis (skin irritation), eczema (thick, dry, and itchy skin), insect bites, etc.

✔️ Pharmacology

Permethrin is a type of pediculicide and scabicide that belongs to the pyrethroid class of compounds. It works by paralyzing and ultimately killing insects, including lice and mites. Permethrin achieves this by blocking the inflow of sodium ions through nerve cell membrane channels, which leads to a delay in repolarization.

Crotamiton has antipruritic properties, meaning it helps relieve itching, and it also possesses scabicidal activity against Sarcoptes scabei, the mite responsible for causing scabies. Additionally, it is an effective pediculicide, meaning it can eliminate lice.

✔️ Dosage & Administration of Lorix Plus Lotion

Adult: Permethrin & Crotamiton lotion is suitable for adults, children of 2 months of age and above, and the elderly. It is for external use only and should not be applied to broken skin, mucous membranes, or near the eyes. Permethrin & Crotamiton lotion should be applied to the skin that is clean, dry, and cool. It should not be used immediately after a hot bath. Permethrin & Crotamiton lotion is intended for a single application over the whole body. Permethrin & Crotamiton lotion should be left on for at least 8 hours. Reapply the lotion to the hands if they are washed within 8 hours of treatment. The whole body should be washed thoroughly 8-12 hours after application. Adults & children over 2 years: Apply the lotion over the whole body but not the head and face. Pay particular attention to the areas between fingers and toes, under nails, wrists, armpits, external genitalia, breasts, and buttocks.

The elderly: Apply the lotion over the whole body including the neck, face, ears, and scalp. Pay particular attention to the areas between fingers and toes, under nails, wrists, armpits, external genitalia, breasts, and buttocks. Avoid the area close to the eyes.

Children under 2 years: Children under 2 years should only be treated under medical supervision. Apply the lotion over the whole body including the neck, face, ears, and scalp. Pay particular attention to the areas between fingers and toes, under nails, wrists, armpits, palms of hands, and soles of feet, external genitals, and buttocks. Avoid the area around the mouth where the lotion could be licked off and the area around the eyes

Administration:

• Lotion should be applied to clean, dry skin.
• If the body is hot due to a warm bath or any other reason, the skin should be allowed to cool. It should be applied to the whole body excluding the head.
• The whole body should be washed thoroughly 8-12 hours after treatment. On the next day, clothes and bed sheets should be cleaned with warm water.
• The lotion should be applied if the lotion is washed out by water.
• Other members of the family should use this lotion as a preventive in the same way due to its highly contagious effects.
• The lotion should not be applied to the vicinity of the mouth and areas close to the eyes.

✔️ Interaction

It is not recommended to use corticosteroid therapy for eczematous-like responses before treating scabies with permethrin. This is because corticosteroids can suppress the immune response to the mite, which may increase the risk of worsening the scabies infestation. However, the likelihood of interactions between the two therapies that could result in intensified side effects or reduced effectiveness is low.

✔️ Contraindications

In individuals with known allergies to permethrin or crotamiton, the combination of 5% permethrin and 10% crotamiton is contraindicated.

✔️ Pregnancy & Lactation

Because there is no experience to assess the safety of permethrin and crotamiton in pregnancy, it is not advised during pregnancy, particularly in the first three months. It is unknown whether the active ingredient enters breast milk. Nursing moms should avoid using it on their nipples.

✔️ Precautions & Warnings

• Keep this lotion out of the reach of children.
• This lotion is only for external use. Nursing personnel who use this lotion on a regular basis may want to wear gloves to avoid hand discomfort.
• Avoid making eye contact.
• The lotion has the potential to irritate the eyes. If lotion gets into your eyes, quickly rinse them with water.
• Lorix Plus Lotion is not recommended for use in infants below 2 months of age. Your doctor will give the right dose depending on your child’s age, body weight, and disease condition. Consult with your doctor before using.
• Lorix Plus Lotion should be used with caution in elderly patients above 70 years of age.

✔️ Storage Conditions

Keep cold (nothing should be stored over 25° C, and nothing should be frozen) and away from light.